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Aims of the STOP study

What are the aims of the STOP study?

Some children and adolescents have conditions that predispose them to suicidality. Medications used to treat medical or psychiatric conditions (some also associated with suicidal risk) may elevate suicidal thoughts or behaviors in a small proportion of patients. Clinicians treating children and adolescents, the patients themselves and their families need to know more about medication-related suicidality (MRS).

Objectives

The STOP study aims to respond to different questions:
What are the best means to monitor MRS?
Is MRS different from suicidality related to the illness?
What biological, psycho-social or illness-related factors put some patients at high risk for MRS? What factors are likely to protect patients from MRS?

This assessment methodology will be used in three clinical samples to identify characteristic features of medication-related suicidality (MRS): children and adolescents receiving an atypical antipsychotic, children receiving fluoxetine for depression and children treated with montelukast for bronchial asthma. These medications were targeted because they have been related to suicidality.

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